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00000000DF
is most prevalent in adults, while DHF is more
prevalent in children. In 1975, 64.7 per cent of dengue
cases were in the under 15 years age group, but in the
peak year of 1982 only 42.5 per cent of cases were in
this age group. Similarly for mortality, 51.4 per cent
of deaths in 1982 occurred in people over 15 years,
whereas in the past it was rare for adults to die of
dengue disease. The disease has been showing a milder
spectrum with less mortality since 1984. The decline
in mortality can be attributed to increased awareness
of the disease, early medical attention and changing
patterns of the disease. More deaths have occurred among
the Chinese and this can be attributed to their lifestyle,
customs and beliefs, which delay them from seeking proper
medical attention and referral.
00000000The
two vectors of dengue in Malaysia are A. aegypti
and A. albopictus. Aedes aegypit is a domiciliary
mosquito and is found both inside and outside the home.
It is usually associated with DHF in urban settings.
Aedes albopictus, a local species, is prevalent in peri-urban
areas and is associated with dengue fever.
00000000The
density of the vector mosquitoes is related to climatic
conditions and the habit of storing water. Aedes
aegypti prefers clean clear water with low oxygen
partial pressure e.g. rainwater. The Aedes premise index
and the Breteau or container index are used to monitor
the density of mosquitoes for preventive actions. Periodic
house inspections and entomological surveys carried
out under existing law (Destruction of Disease Bearing
Insect Act, 1975) have not generated useful indices.
Outbreaks tend to occur in areas with high Aedes densities.
However, areas with low Aedes indices (of five per cent
or less) are not exempt.
|
year
|
case
|
death
|
CFR
(%)
|
|
1992
|
5,473
|
24
|
0.44
|
|
1993
|
5,615
|
23
|
0.41
|
|
1994
|
3,133
|
13
|
0.41
|
|
1995
|
6,543
|
28
|
0.43
|
|
1996
|
14,255
|
32
|
0.22
|
Data from WHO/WPR 1997
Australia
00000000Aedes
aegypti is believed to have become established in northern
Australian settlements in the 1860s. Lumley and Taylor(27)
documented regular epidemics of dengue, commencing in
1873 when eight clinical cases were imported into Sydney
from Mauritius. Local transmission was probably first
recorded from Townsville in 1879 but the outbreaks on
the Charters Towers gold fields during 1885 - 1886 are
better remembered because of their extensiveness and
the description by Hare(28) of what is considered to
be the first DHF case. By 1926, clinical dengue had
been reported in four Australian states, coincident
with the distribution of A. aegypti. Lumbey and Taylor(27)
reported on the large outbreak of dengue in 1941 - 1944,
which spread from Queensland to New South Wales due
to the movement of armed services personnel. From 1954
- 1955, north Queensland was stricken by DEN-3 virus
and some 15 000 of 40 000 residents of Townsville were
infected(29). In ensuing years, A. argypti was reduced
and this led to the decline of dengue in the country.
00000000From
1981 - 1983, there was an upsurge of dengue activity
in Queensland. Breteau indices of over 100 were not
uncommon, a level said to be twice that of the high
risk category for yellow fever(30). It has been estimated
that at least 3000 infections of DEN-1 occurred in 19
north Queensland towns. In Cairns, it was noted that
13 of 98 patients showed some haemorrhagic manifestations
but these were not severe enough to be classified as
DHF. A control programme has been mounted against the
mosquito vector but the possibility still exists that
the other dengue serotypes will be introduced into Australia.
 
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